Funding (subcontract): National Institute on Aging, 2013-2015 (1st Amendment)
The University of Michigan contract includes work on Cores C, and on Projects 3 and 5. These components are described below, as are the roles of key personnel at University of Michigan.
Core C - Modeling Core: We will build models of disease processes for common diseases of the elderly, synthesizing this information at the patient level. These models will focus on care for cardiovascular disease (Project 3), cancer (Project 4), and mood disorders (Project 5). To ensure that outputs are comparable across models, Core C will develop and implement a standardized set of assumptions for these disease models.
Project 3- The Value of Interventions for Cardiovascular Disease : This project will assess trends in the value of cardiovascular disease interventions over time. We will build models estimating the value of spending on coronary heart disease (CHD) and stroke. This will be done by documenting trends, developing microsimulation models relating trends in risk factors and use of medical therapies to trends in health. We will integrate the coronary heart disease and stroke models to obtain a single model of cardiovascular disease using dynamic Influence Diagrams to evaluate a potential method for integrating multiple diseases in the future.
Project 5- The Value of Interventions for Depression: We will examine whether the value of depression care has changed over time using cross-sectional and longitudinal data from the Health and Retirement Study. Knowledge of the value of depression care can be of great use for making and refining mental health care policy in the US.