Race/Ethnicity, DNA Methylation, and Disparities in Cardiovascular Mortality: NHANES 1999-2002

a MiCDA Research Project Description

Investigators: Belinda L. Needham, Jennifer A. Smith, Xiang Zhou, Bhramar Mukherjee

Funding: National Institute on Minority Health and Health Disparities, 2017-2022 (1 R01 MD 011721 01)

US blacks are more likely to die from cardiovascular disease (CVD) than US whites. This study will help determine whether black/white differences in DNA methylation help explain why blacks are more likely than whites to die from CVD. Because DNA methylation is potentially modifiable, results from this work could be used to develop interventions to improve cardiovascular health and reduce disparities in cardiovascular death.

Research Signature Theme:

Health and well-being in later life: Disparities