Multimorbidity of four cardiometabolic and chronic pulmonary disease groups: prevalence and attributable fraction in US adults, 2007-2012
Staimez, Lisa, Melissa Y. Wei, Min Kim, KM Venkat Narayan, and Sharon Saydah. 2017. "Multimorbidity of four cardiometabolic and chronic pulmonary disease groups: prevalence and attributable fraction in US adults, 2007-2012." Journal of Comorbidity, 7(1): 22-32.
Cardiometabolic and chronic pulmonary diseases may be associated with modifiable risk factors that can be targeted to prevent multimorbidity. We estimated the prevalence of multimorbidity across four cardiometabolic and chronic pulmonary disease groups; compared the prevalence of multimorbidity to monomorbidity and no disease; and quantified population attributable fractions (PAFs) for modifiable risk factors of multimorbidity. Among 16,676 adults, the age-standardized prevalence of multimorbidity was 9.3%; with multimorbidity occurring in 34.8% of adults aged 65-79 years and in 1.5% of adults aged 18-40 years. Multimorbidity was greatest among the poorest versus non-poorest adults and among blacks versus other races/ethnicities. Multimorbidity was also greater in adults with obesity, hypertension, and low HDL cholesterol. Risk factors with greatest PAFs were hypertension (38.8%) and obesity (19.3%). Our results suggest that reducing hypertension and obesity might yield over 50% reduction in the prevalence of multimorbidity of these diseases.